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March 4, 2025
Profhilo vs. dermal fillers, bio-stimulators, and skin boosters - discover how Profhilo uniquely rejuvenates skin elasticity and hydration, naturally.
It’s exciting to see just how far the world of aesthetics has come from simply addressing wrinkles. Now, we’re able to improve skin texture, hydration, and overall appearance thanks to an ever-evolving range of advanced injectables. From fillers and skin boosters to biostimulators and polynucleotides, each treatment offers unique benefits.
However, with so many treatments now available, it’s easy for patients (especially new ones) to become overwhelmed when deciding what’s best for your skin.
One treatment that’s gained significant attention due to its unique formulation and ability to bio-remodel the skin without adding volume is Profhilo. While traditional fillers restore lost volume and skin boosters give that lovely surface hydration, Profhilo takes a slightly different path. It works on a deeper level to really encourage your skin's natural elasticity and firmness. It also contributes to hydration, but its primary focus is on that underlying support structure.
Let's take a closer look at what makes this treatment stand out.
Profhilo isn’t a filler, a skin booster, or a collagen-stimulating injectable. It’s considered a bio-remodeller, and is truly in a league of its own. With one of the highest concentrations of stabilised hyaluronic acid available, it works differently from traditional injectables. Unlike fillers, which stay in specific areas to add volume, Profhilo spreads beneath the skin, deeply hydrating and stimulating collagen and elastin production.
Once injected, it disperses naturally, encouraging fibroblasts – the cells responsible for producing collagen and elastin – to kick into action. The results are enhanced skin texture, firmness, and smoothness that leaves your complexion looking naturally refreshed and brighter. Over time, your skin becomes healthier, more hydrated, and more resilient to aging, without any risk of an overdone or unnatural appearance.
When it comes to injectables, dermal fillers are usually the first thing people think of. They’re designed to restore lost volume, contour the face, and soften wrinkles. Dermal fillers stay in specific areas, providing lift and structure where needed – like plumping lips, lifting cheeks, or defining the jawline.
Profhilo, on the other hand, doesn’t add volume. Instead, it spreads beneath the skin, triggering collagen production and deep hydration for a more refined, rejuvenated look. While fillers help with lift, structure, and contouring, Profhilo is all about improving skin laxity, boosting hydration, and enhancing overall skin quality.
If you’re concerned about hollow cheeks or deep wrinkles, fillers may be the better choice. But if your skin is starting to feel thin or dehydrated, Profhilo is ideal for restoring elasticity and youthfulness.
Biostimulators like Sculptra work quite differently from Profhilo. Instead of using hyaluronic acid, they contain collagen-stimulating compounds that gradually restore volume and skin thickness over time. Sculptra contains poly-L-lactic acid, which encourages your body to produce more collagen, leading to a slow and natural lifting and volumising effect.
While Sculptra is great for treating significant volume loss, it doesn’t provide the deep hydration that Profhilo does. Plus, results take longer to appear since the body needs time to generate new collagen – usually several months.
If you're after instant hydration, skin tightening, and a smoother complexion, Profhilo is the better choice. But if your main concern is severe volume loss and sagging, a biostimulator like Sculptra might be more suitable. You can understand more about Sculptra treatments here.
Polynucleotide injectables are becoming a go-to choice for those looking to repair and regenerate their skin from the inside out. These injectables work at a cellular level to improve microcirculation and enhance tissue quality, making them especially beneficial for sun-damaged or delicate skin.
While Profhilo is known for its hydration and collagen-boosting benefits, polynucleotides do go a step further by actively repairing the skin at a cellular level. This makes them ideal for under-eye rejuvenation and conditions like acne scarring, post-inflammatory pigmentation, or skin that has been weakened by previous treatments.
Polynucleotides can also be used in delicate areas where Profhilo is not typically suitable, such as the under-eye area and forehead, making it a more versatile option for full-face rejuvenation.
That said, if you're after an immediate boost in hydration and skin plumping, Profhilo might be the better option for a quick firming effect.
Skin boosters, like Sunekos, are often compared to Profhilo since they both contain hyaluronic acid and aim to improve skin hydration. The main difference is that Sunekos contains two different molecular weights of hyaluronic acid combined with six amino acids in a perfectly balanced ratio. This unique formula enhances the extracellular matrix and improves cell signalling, leading to better skin regeneration and long-term structural support.
Unlike Profhilo, which spreads evenly beneath the skin, skin boosters are injected in smaller doses across the treatment area and work more on the surface level.
Sunekos typically requires several sessions to see optimal results, whereas Profhilo only requires two treatments spaced about four weeks apart. Plus, Profhilo offers longer-lasting collagen stimulation, making it a great option for patients looking for deeper, more structural improvements in their skin’s firmness. You can find out more information about Sunekos treatments here.
Profhilo is particularly popular among patients in their 30s to 50s who are starting to notice the first signs of aging. However, it can also be a great option for younger individuals looking to maintain their skin and prevent future concerns, as well as older patients who want to improve skin firmness without turning to more invasive treatments.
Profhilo is an excellent aid for the skin during extreme temperatures, helping to combat dehydration in both harsh winter cold and intense summer heat. It is particularly beneficial after prolonged sun exposure, whether from summer beach holidays or winter ski trips, where the sun can be equally damaging. Additionally, it supports skin health for those whose diet (high alcohol and sugar consumption) and lifestyle choices (such as smoking) compromise skin quality, helping to restore hydration and resilience.
Profhilo truly stands out as an injectable treatment, sitting perfectly between fillers, biostimulators, and skin boosters. It offers hydration, tightening, and collagen stimulation without adding volume or changing your facial features. If you're looking to improve your skin’s overall quality, reduce laxity, and boost elasticity, Profhilo is a highly effective choice with minimal downtime. But as with any treatment, the best approach is a tailored one.
Book your consultation with the Anti Wrinkle Clinic today and let Dr Yiannis help you find the perfect treatment for your skin concerns and long-term goals.
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